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PERISTALTIC PUMP APPLICATIONS
CHROMATOGRAPHIC TECHNIQUES
Compact and stackable LAMBDA peristaltic pumps are very well suitable for chromatography (together with LAMBDA OMNICOLL fraction collector and autosampler or as a stand alone instrument):
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Liquid chromatography, LC
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Taking samples
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Automatic liquid handling
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Collecting fractions / sampling
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Pouring gradient gels
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Gradient formation
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Column saturation with upward pump flow
FERMENTATION AND CELL CULTURE RESEARCH
LAMBDA Peristaltic pumps are specially developed for long term continuous processes like in fermentations and cell cultures. With the sterilzable tubing, the peristaltic pump can be used for sterile and aseptic processes:
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Feed pump and harvest pump (fed-batch culture, continuous culture, chemostat, turbidostat, perfusion)
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pH control (addition of acid, base, buffers)
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Antifoam control (addition of antifoam agent)
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Sampling at particular time interval
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Feed flow profile (exponential feed rate, automatic switch ON/OFF)
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Aseptic sample addition/injection
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Controlled addition of nutrients, minerals, trace elements
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Media dispenser
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Process optimization with C-feed in fed batch
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Pump media with foot switch for filling agar plates
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Follow growth kinetics
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Quantify the metabolic activity of the culture
CHEMICAL & BIOCHEMICAL REACTIONS
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Precise addition of liquids for titration
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Visualisation of reaction velocity – hydrolysis of amides, esters, anhydrides, etc
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Controlled addition of reactants during exothermic reactions (thermostat)
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Acid or base addition to maintain pH (pH stat)
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Control of oxidation and reduction potential
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Measurement of enzyme activity of numerous enzymes (eg. esterases, acylases, lipases, proteases and others)
SINGLE USE SYSTEM & PHARMACEUTICAL RESEARCH
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Since it is a contamination sensitive process, LAMBDA peristaltic pumps can be used for precise addition or removal of the desired liquid
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Sterile filtration
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Dosing cell suspension
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Process validation and drug trails